ELL2 antibody (AA 253-352)

Catalog No. ABIN7266925

Product Details anti-ELL2 Antibody

Target: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Binding Specificity: AA 253-352

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: ELL2 Rabbit pAb

Sequence: SKDLSYTLKD YVFKELQRDW PGYSEIDRRS LESVLSRKLN PSQNAAGTSR SESPVCSSRD AVSSPQKRLL DSEFIDPLMN KKARISHLTN RVPPTLNGHL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 253-352 of human ELL2 (NP_036213.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ELL2

Target: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Alternative Name: ELL2 (ELL2 Products)

Synonyms: cb244 antibody, fb78f03 antibody, sb:cb244 antibody, im:3814960 antibody, wu:fb78f03 antibody, xell2 antibody, MGC82755 antibody, ELL2 antibody, elongation factor for RNA polymerase II 2 antibody, elongation factor, RNA polymerase II, 2 antibody, elongation factor, RNA polymerase II 2 S homeolog antibody, elongation factor, RNA polymerase II 2 antibody, elongation factor RNA polymerase II 2 antibody, ELL2 antibody, ell2 antibody, ell2.S antibody, Ell2 antibody

Background: Elongation factor component of the super elongation complex (SEC, a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC, a complex required to regulate small nuclear RNA (snRNA gene transcription by RNA polymerase II and III. Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A site choice and exon skipping, as well as immunoglobulin heavy chain (IgH alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.,ELL2,Epigenetics & Nuclear Signaling,Transcription Factors,ELL2

Gene ID: 22936

UniProt: O00472