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EXOSC7 antibody

EXOSC7 Reactivity: Human WB Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7267065
  • Target See all EXOSC7 Antibodies
    EXOSC7 (Exosome Component 7 (EXOSC7))
    Reactivity
    • 29
    • 22
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 24
    • 5
    Rabbit
    Clonality
    • 25
    • 4
    Monoclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXOSC7 antibody is un-conjugated
    Application
    • 13
    • 13
    • 12
    • 6
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    EXOSC7 Rabbit mAb
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human EXOSC7.
    Isotype
    IgG
    Top Product
    Discover our top product EXOSC7 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    EXOSC7 (Exosome Component 7 (EXOSC7))
    Alternative Name
    EXOSC7 (EXOSC7 Products)
    Synonyms
    EXOSC7 antibody, zgc:110717 antibody, EAP1 antibody, RRP42 antibody, Rrp42p antibody, hRrp42p antibody, p8 antibody, 2610002K22Rik antibody, AV212732 antibody, mKIAA0116 antibody, exosome component 7 antibody, exosome component 7 S homeolog antibody, exosc7 antibody, EXOSC7 antibody, exosc7.S antibody, Exosc7 antibody
    Background
    Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR and/or Ig variable region somatic hypermutation (SHM by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9 is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.,EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8, exosome component 7,Epigenetics & Nuclear Signaling,EXOSC7
    Molecular Weight
    32kDa
    Gene ID
    23016
    UniProt
    Q15024
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