HIST1H2AE antibody

Catalog No. ABIN7267703

Product Details anti-HIST1H2AE Antibody

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HIST1H2AE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purpose: Histone H2A Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Histone H2A

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HIST1H2AE

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Alternative Name: HIST1H2AE (HIST1H2AE Products)

Synonyms: H2A.1 antibody, H2A.2 antibody, H2A/a antibody, H2AFA antibody, histone cluster 1 H2A family member e antibody, HIST1H2AE antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],H2A.1, H2A.2, H2A/a, H2AFA,HIST1H2AE

Molecular Weight: 14kDa

Gene ID: 3012

UniProt: P04908

Pathways: Telomere Maintenance