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IL-18 antibody

IL18 Reactivity: Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7267992
  • Target See all IL-18 (IL18) Antibodies
    IL-18 (IL18) (Interleukin 18 (IL18))
    Reactivity
    • 68
    • 36
    • 31
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 104
    • 24
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 102
    • 25
    • 2
    Polyclonal
    Conjugate
    • 63
    • 16
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IL-18 antibody is un-conjugated
    Application
    • 78
    • 45
    • 35
    • 31
    • 26
    • 25
    • 12
    • 11
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purpose
    IL18 Rabbit pAb
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of Mouse IL18.
    Isotype
    IgG
    Top Product
    Discover our top product IL18 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IL-18 (IL18) (Interleukin 18 (IL18))
    Alternative Name
    IL18 (IL18 Products)
    Synonyms
    Igif antibody, Il-18 antibody, IL-18 antibody, IGIF antibody, ChIL-18 antibody, IL-1g antibody, IL1F4 antibody, IL18 antibody, interleukin 18 antibody, Il18 antibody, IL18 antibody
    Background
    Interleukin-18 (L-18) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.,Ig, Il-, Igif, Il-18,IL18
    Molecular Weight
    22kDa
    Gene ID
    16173
    UniProt
    P70380
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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