KREMEN2 antibody (AA 200-360)

Catalog No. ABIN7268149

Product Details anti-KREMEN2 Antibody

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Binding Specificity: AA 200-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KREMEN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: KREMEN2 Rabbit pAb

Sequence: GQLCGGDGRL GVYEVSVGSC QGNWTAPQGV IYSPDFPDEY GPDRNCSWAL GPPGAALELT FRLFELADPR DRLELRDAAS GSLLRAFDGA RPPPSGPLRL GTAALLLTFR SDARGHAQGF ALTYRGLQDA AEDPEAPEGS AQTPAAPLDG ANVSCSPRPG A

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human KREMEN2 (NP_078783.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KREMEN2

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Alternative Name: KREMEN2 (KREMEN2 Products)

Synonyms: krm2 antibody, KREMEN2 antibody, MGC147633 antibody, KRM2 antibody, 2900054E04Rik antibody, Krm2 antibody, kringle containing transmembrane protein 2 S homeolog antibody, kringle containing transmembrane protein 2 antibody, kremen2.S antibody, KREMEN2 antibody, kremen2 antibody, Kremen2 antibody

Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.,KREMEN2,KRM2,Stem Cells,KREMEN2

Molecular Weight: 40kDa/42kDa/44kDa/45kDa/48kDa

Gene ID: 79412

UniProt: Q8NCW0

Pathways: WNT Signaling