PGC1 alpha + beta antibody

Catalog No. ABIN7269258

Product Details

Target: PGC1 alpha + beta

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Purpose: PGC1α/β Rabbit mAb

Cross-Reactivity: Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PGC1alpha/beta.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: PGC1 alpha + beta

Alternative Name: PGC1alpha/beta

Synonyms: LEM6 antibody, PGC-1(alpha) antibody, PGC-1v antibody, PGC1 antibody, PGC1A antibody, PPARGC1 antibody, A830037N07Rik antibody, ENSMUSG00000079510 antibody, Gm11133 antibody, PGC-1 antibody, Pgc-1alpha antibody, Pgc1 antibody, Pgco1 antibody, Ppargc1 antibody, PPARG coactivator 1 alpha antibody, peroxisome proliferative activated receptor, gamma, coactivator 1 alpha antibody, PPARGC1A antibody, Ppargc1a antibody

Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.,LEM6,PGC-1(alpha),PGC-1alpha,PGC-1v,PGC1,PGC1A,PPARGC1,ERRL1,PERC,PGC-1(beta),PGC1B,PGC1α/β

Molecular Weight: 113kDa

Gene ID: 10891, 133522

UniProt: Q9UBK2, Q86YN6