PKM1-Specific antibody
Reactivity: Human
WB, IF, IHC
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- PKM1-Specific
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Purpose
- PKM1-specific Rabbit pAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human PKM1-specific.
- Isotype
- IgG
-
-
- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- PKM1-Specific
- Background
- This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.,PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,PKM1-specific
- Molecular Weight
- 56kDa/57kDa/58kDa
- Gene ID
- 5315
- UniProt
- P14618
-
You are here:
