PRELP antibody

Catalog No. ABIN7269551

Product Details anti-PRELP Antibody

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRELP antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PRELP Rabbit pAb

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human PRELP.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRELP

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Alternative Name: PRELP (PRELP Products)

Synonyms: 7330409J17Rik antibody, SLRR2A antibody, MST161 antibody, MSTP161 antibody, proline arginine-rich end leucine-rich repeat antibody, proline and arginine rich end leucine rich repeat protein antibody, Prelp antibody, PRELP antibody

Background: The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008],MST161,MSTP161,SLRR2A,PRELP,Cell Biology & Developmental Biology,Cytoskeleton,Epigenetics & Nuclear Signaling,Extracellular Matrix,Extracellular Matrix_Bone,Signal Transduction,PRELP

Gene ID: 5549

UniProt: P51888

Pathways: Glycosaminoglycan Metabolic Process