PIAS1 antibody

Catalog No. ABIN7269622

This Rabbit Monoclonal antibody specifically detects PIAS1 in WB. It exhibits reactivity toward Human.

Quick Overview for PIAS1 antibody (ABIN7269622)

Target: PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PIAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIAS1 Antibody

Purpose: PIAS1 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PIAS1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIAS1

Target: PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))

Alternative Name: PIAS1

Background: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],DDXBP1, GBP, GU/RH-II, ZMIZ3,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Nuclear Receptor Signaling,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,PIAS1

Molecular Weight: 76kDa

Gene ID: 8554

UniProt: O75925

Pathways: JAK-STAT Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C