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PRTN3 antibody (pArg3)
PRTN3
Reactivity: Human
WB, IF
Host: Rabbit
Monoclonal
unconjugated
Product Details anti-PRTN3 Antibody
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Target
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PRTN3
(Proteinase 3 (PRTN3))
Binding Specificity
All epitopes for PRTN3 antibodies
pArg3
Reactivity
All reactivities for PRTN3 antibodies
Human
Host
All hosts for PRTN3 antibodies
Rabbit
Clonality
All clonalities for PRTN3 antibodies
Monoclonal
Conjugate
All conjugates for PRTN3 antibodies
This PRTN3 antibody is un-conjugated
Application
All applications for PRTN3 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purpose
Proteinase 3/PR3 Rabbit mAb
Cross-Reactivity
Human, Mouse
Characteristics
Monoclonal Antibodies
Purification
Affinity purification
Immunogen
A synthesized peptide derived from human Proteinase 3/PR3
Isotype
IgG
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Discover our top product PRTN3 Primary Antibody
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PRTN3
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Target
PRTN3
(Proteinase 3 (PRTN3))
Alternative Name
PRTN3 (PRTN3 Products )
Synonyms
ela2 antibody, MGC132250 antibody, ACPA antibody, AGP7 antibody, C-ANCA antibody, CANCA antibody, MBN antibody, MBT antibody, NP-4 antibody, NP4 antibody, P29 antibody, PR-3 antibody, PR3 antibody, mPR3 antibody, proteinase 3 L homeolog antibody, proteinase 3 antibody, prtn3.L antibody, PRTN3 antibody, Prtn3 antibody
Background
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.,ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Extracellular Matrix_Collagen,Signal Transduction,PRTN3
Molecular Weight
27kDa
Gene ID
5657
UniProt
P24158
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