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RCCD1 antibody (AA 230-360)
RCCD1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RCCD1 Antibody
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Target
See all RCCD1 products
RCCD1
(RCC1 Domain Containing 1 (RCCD1))
Binding Specificity
AA 230-360
Reactivity
Human
Host
All hosts for RCCD1 antibodies
Rabbit
Clonality
All clonalities for RCCD1 antibodies
Polyclonal
Conjugate
All conjugates for RCCD1 antibodies
This RCCD1 antibody is un-conjugated
Application
All applications for RCCD1 antibodies
Western Blotting (WB)
Purpose
RCCD1 Rabbit pAb
Sequence
DIYIWGWNES GQLALPTRNL AEDGETVARE ATELNEDGSQ VKRTGGAEDG APAPFIAVQP FPALLDLPMG SDAVKASCGS RHTAVVTRTG ELYTWGWGKY GQLGHEDTTS LDRPRRVEYF VDKQLQVKAV T
Cross-Reactivity
Human, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 230-360 of human RCCD1 (NP_001017919.1).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for RCCD1
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Target
RCCD1
(RCC1 Domain Containing 1 (RCCD1))
Alternative Name
RCCD1 (RCCD1 Products )
Synonyms
5830436H09 antibody, E430018M08Rik antibody, RCC1 domain containing 1 antibody, RCCD1 antibody, Rccd1 antibody
Background
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT, potentially through the inhibition of KDM8.,RCCD1,Cell Biology & Developmental Biology,RCCD1
Gene ID
91433
UniProt
A6NED2
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