SGEF antibody (AA 592-871)

Catalog No. ABIN7269968

Product Details anti-SGEF Antibody

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Binding Specificity: AA 592-871

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGEF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: ARHGEF26 Rabbit pAb

Sequence: ICQKTPKDSP KYEVCKRALK EVSKLVRLCN EGARKMERTE MMYTINSQLE FKIKPFPLVS SSRWLVKRGE LTAYVEDTVL FSRRTSKQQV YFFLFNDVLI ITKKKSEESY NVNDYSLRDQ LLVESCDNEE LNSSPGKNSS TMLYSRQSSA SHLFTLTVLS NHANEKVEML LGAETQSERA RWITALGHSS GKPPADRTSL TQVEIVRSFT AKQPDELSLQ VADVVLIYQR VSDGWYEGER LRDGERGWFP MECAKEITCQ ATIDKNVERM GRLLGLETNV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 592-871 of human ARHGEF26 (NP_056410.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SGEF

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Alternative Name: ARHGEF26 (ARHGEF26 Products)

Synonyms: SGEF antibody, AI303572 antibody, AW491953 antibody, 4631416L12Rik antibody, 8430436L14Rik antibody, RGD1562559 antibody, Sgef antibody, CSGEF antibody, HMFN1864 antibody, Rho guanine nucleotide exchange factor (GEF) 26 antibody, Rho guanine nucleotide exchange factor 26 antibody, Arhgef26 antibody, ARHGEF26 antibody

Background: This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],ARHGEF26,CSGEF,HMFN1864,SGEF,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Signal Transduction,ARHGEF26

Molecular Weight: 48kDa/88kDa/97kDa

Gene ID: 26084

UniProt: Q96DR7