ARHGEF2 antibody (pSer886)

Catalog No. ABIN7269976

Product Details anti-ARHGEF2 Antibody

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Binding Specificity: pSer886

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Phospho-ARHGEF2-S886 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S886 of human ARHGEF2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Alternative Name: ARHGEF2 (ARHGEF2 Products)

Synonyms: MGC82333 antibody, MGC86214 antibody, MGC75855 antibody, AA408978 antibody, GEF antibody, GEF-H1 antibody, GEFH1 antibody, LFP40 antibody, Lbcl1 antibody, Lfc antibody, P40 antibody, mKIAA0651 antibody, GEF-H1/LFC antibody, Rho/Rac guanine nucleotide exchange factor 2 antibody, Rho/Rac guanine nucleotide exchange factor 2 S homeolog antibody, rho/rac guanine nucleotide exchange factor (GEF) 2 antibody, ARHGEF2 antibody, arhgef2.S antibody, arhgef2 antibody, Arhgef2 antibody

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009],GEF,GEF-H1,GEFH1,LFP40,P40,ARHGEF2,NEDMHM,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microtubules,G protein signaling,G protein signaling_Small G proteins,Protein phosphorylation,Signal Transduction,ARHGEF2

Molecular Weight: 108kDa/111kDa

Gene ID: 9181

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling