SIGMAR1 antibody (AA 31-80)

Catalog No. ABIN7270296

The Rabbit Polyclonal anti-SIGMAR1 antibody (ABIN7270296) specifically detects SIGMAR1 in WB. The antibody is reactive with Human samples.

Quick Overview for SIGMAR1 antibody (AA 31-80) (ABIN7270296)

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGMAR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIGMAR1 Antibody

Binding Specificity: AA 31-80

Purpose: SIGMAR1 Rabbit pAb

Sequence: GTQSFVFQRE EIAQLARQYA GLDHELAFSR LIVELRRLHP GHVLPDEELQ

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-80 of human SIGMAR1 (NP_005857.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SIGMAR1

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Alternative Name: SIGMAR1

Background: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.,SIGMAR1,ALS16,DSMA2,OPRS1,SIG-1R,SR-BP,SR-BP1,SRBP,hSigmaR1,sigma1R,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Heart,Cardiac metabolism,Hypertrophy,SIGMAR1

Molecular Weight: 11kDa/21kDa/22kDa/25kDa

Gene ID: 10280

UniProt: Q99720

Pathways: SARS-CoV-2 Protein Interactome