SF3B5 antibody (AA 1-86)

Catalog No. ABIN7270546

Product Details anti-SF3B5 Antibody

Target: SF3B5 (Splicing Factor 3b, Subunit 5, 10kDa (SF3B5))

Binding Specificity: AA 1-86

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: SF3B5 Rabbit pAb

Sequence: MTDRYTIHSQ LEHLQSKYIG TGHADTTKWE WLVNQHRDSY CSYMGHFDLL NYFAIAENES KARVRFNLME KMLQPCGPPA DKPEEN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human SF3B5 (NP_112577.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SF3B5

Target: SF3B5 (Splicing Factor 3b, Subunit 5, 10kDa (SF3B5))

Alternative Name: SF3B5 (SF3B5 Products)

Synonyms: 10kDa antibody, 1110005L13Rik antibody, AU043053 antibody, Sf3b10 antibody, SF3b10 antibody, Ysf3 antibody, splicing factor 3b, subunit 5 antibody, splicing factor 3b subunit 5 antibody, Sf3b5 antibody, SF3B5 antibody

Background: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.,SF3B5,SF3b10,Ysf3,Epigenetics & Nuclear Signaling,SF3B5

Molecular Weight: 10kDa

Gene ID: 83443

UniProt: Q9BWJ5