TCIRG1 antibody

Catalog No. ABIN7384104

The Rabbit Polyclonal anti-TCIRG1 antibody has been validated for IF. It is suitable to detect TCIRG1 in samples from Human, Mouse and Rat.

Quick Overview for TCIRG1 antibody (ABIN7384104)

Target: TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCIRG1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-TCIRG1 Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TCIRG1 (NP_006010.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TCIRG1

Target: TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))

Alternative Name: TCIRG1

Background: TCIRG1,ATP6N1C,ATP6V0A3,Atp6i,OC-116 kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3,This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.

Gene ID: 10312

UniProt: Q13488

Pathways: Transition Metal Ion Homeostasis, Proton Transport