CD31 antibody

Catalog No. ABIN7384347

Product Details anti-CD31 Antibody

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity Purified

Clone: R07-6A1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000 IHC 1:20-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31 (PECAM1 Products)

Synonyms: CD31 antibody, CD31/EndoCAM antibody, GPIIA' antibody, PECA1 antibody, PECAM-1 antibody, endoCAM antibody, C85791 antibody, Cd31 antibody, Pecam antibody, platelet/endothelial cell adhesion molecule 1 antibody, platelet and endothelial cell adhesion molecule 1 antibody, pecam1 antibody, PECAM1 antibody, Pecam1 antibody

Background: Adhesion molecule,CD31,CD31 antigen,CD31 EndoCAM,EndoCAM,FLJ34100,FLJ58394,GPIIA,GPIIA',PECA1,PECA1,Pecam 1,PECAM 1 CD31 EndoCAM,PECAM,PECAM-1,Pecam1,Platelet and endothelial cell adhesion molecule 1,Platelet endothelial cell adhesion molecule,Platelet/endothelial cell adhesion molecule 1,Platelet endothelial cell adhesion molecule-1 (PECAM-1,CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium,making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets,monocytes,neutrophils,natural killer cells,megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion,PECAM-1 functions as a signaling receptor,and is involved in important physiological events such as nitric oxide production,regulation of T-cell immunity and tolerance,leukocyte transendothelial migration and inflammation and angiogenesis .

Molecular Weight:

Observed_MW: 130kDa

Calculated_MW: 83kDa

Gene ID: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization