PAI1 antibody

Catalog No. ABIN7384366

The Rabbit Monoclonal anti-PAI1 antibody (Clone R07-2C3) (ABIN7384366) specifically detects PAI1 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for PAI1 antibody (ABIN7384366)

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PAI1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R07-2C3

Product Details anti-PAI1 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAI1

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Alternative Name: PAI1

Background: Clade E,Endothelial plasminogen activator inhibitor,Nexin,PAI 1,PAI,PAI-1,PAI1,PLANH1,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor type 1,Serine (or cysteine) proteinase inhibitor,Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1,Serpin E1,Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1,Serpin peptidase inhibitor clade E,Serpine 1,SERPINE1,SERPINE1,also named as Plasminogen activator inhibitor type 1 (PAI-1),is a member of the serine protease inhibitor (SERPIN) superfamily. PAI-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA),and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency),and high concentrations of the gene product are associated with thrombophilia.

Molecular Weight:

Observed_MW: 45kDa

Calculated_MW: 45kDa

Gene ID: 5054

UniProt: P05121

Pathways: p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration