STING/TMEM173 antibody
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- Target See all STING/TMEM173 (TMEM173) Antibodies
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This STING/TMEM173 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Affinity Purified
- Clone
- R06-9A7
- Isotype
- IgG
- Top Product
- Discover our top product TMEM173 Primary Antibody
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- Application Notes
- WB 1:500-1:1000 IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Concentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Alternative Name
- Transmembrane Protein 173 (TMEM173 Products)
- Synonyms
- ERIS antibody, MITA antibody, MPYS antibody, NET23 antibody, STING antibody, 2610307O08Rik antibody, Mita antibody, RGD1562552 antibody, transmembrane protein 173 antibody, TMEM173 antibody, Tmem173 antibody
- Background
- Endoplasmic reticulum IFN stimulator,Endoplasmic reticulum interferon stimulator,ERIS,FLJ38577,hMITA,hSTING,Mediator of IRF3 activation,MITA,Mitochondrial mediator of IRF3 activation,MPYS,N terminal methionine proline tyrosine serine plasma membrane tetraspanner,NET23,Stimulator of interferon genes,Stimulator of interferon genes protein,STING,TM173,Tmem173,Transmembrane protein 173,This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 40kDa
Calculated_MW: 42kDa
- Gene ID
- 340061
- UniProt
- Q86WV6
- Pathways
- Activation of Innate immune Response
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