Bcl-2 antibody

Catalog No. ABIN7384553

This Rabbit Polyclonal antibody specifically detects Bcl-2 in WB. It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for Bcl-2 antibody (ABIN7384553)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bcl-2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Bcl-2 Antibody

Purification: Antigen Affinity Purification

Immunogen: Synthetic peptide corresponding to zebrafish BCL-2 conjugated to keyhole limpet haemocyanin.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-2000, IP: 3 μg/sample, IF: 1:100-200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.1 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: Bcl-2

Background: Bcl-2, PPP1R50, BCL2,Bcl-2 (B-cell lymphoma 2), is the founding member of the Bcl-2 family of regulator proteins that regulate cell death (apoptosis), by either inducing (pro-apoptotic) or inhibiting (anti-apoptotic) apoptosis. In mammalians, it is found to be associated with

Molecular Weight:

Observed_MW: 26kDa

Calculated_MW: 26kDa

Gene ID: 570772

UniProt: Q564A4

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling