Recombinant CD47 antibody (AA 19-142)

Catalog No. ABIN7449426

This anti-CD47 antibody is a Rabbit Monoclonal antibody detecting CD47 in WB, IHC and ICC. Suitable for Human.

Quick Overview for Recombinant CD47 antibody (AA 19-142) (ABIN7449426)

Target: CD47

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD47 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR131H

Product Details anti-CD47 Antibody

Binding Specificity: AA 19-142

Purpose: Rabbit anti-CD47 Recombinant Monoclonal Antibody [BLR131H]

Immunogen: residues 19-142 (ECD)

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD47

Target: CD47

Alternative Name: CD47

Background: Background: CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. [taken from the Universal Protein Resource (UniProt) Q08722].

Gene ID: 961

NCBI Accession: NP_001768

UniProt: Q08722