FAK antibody (AA 325-375)

Catalog No. ABIN7452326

The Rabbit Polyclonal anti-FAK antibody is suitable to detect FAK in samples from Human. It has been validated for IP.

Quick Overview for FAK antibody (AA 325-375) (ABIN7452326)

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAK antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-FAK Antibody

Binding Specificity: AA 325-375

Purpose: Rabbit anti-FAK Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,X. laevis,Chicken

Purification: Affinity Purified

Immunogen: between AA 325 and 375

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-FAK antibody ABIN7451778.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FAK

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Alternative Name: FAK

Background: Background: Focal adhesion kinase (FAK) is a non-receptor protein-tyrosine kinase that localizes to the cytoplasm and is concentrated in focal adhesions, macromolecular assemblies that form a communicative link between the cell and the extracellular matrix. FAK signaling is stimulated by integrin-mediated responses, as well as growth factors, chemokines, and G-protein-linked receptors. FAK signaling influences cell motility, invasion, and survival.

Gene ID: 5747

NCBI Accession: NP_005598

UniProt: Q05397

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling