Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 49-1456) antibody (APC)

Catalog No. ABIN8031064

The APC-conjugated Rabbit Polyclonal anti-Regulating Synaptic Membrane Exocytosis 1 antibody (ABIN8031064) specifically detects Regulating Synaptic Membrane Exocytosis 1 in WB, ELISA and IHC. The antibody is reactive with Rat and Mouse samples.

Quick Overview for Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 49-1456) antibody (APC) (ABIN8031064)

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: APC

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 49-1456

Purpose: Anti-RIM1/RIMS1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RIM1/RIMS1 recombinant protein (Position: K49-E1456).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Alternative Name: RIMS1

Background:

Background: The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: regulating synaptic membrane exocytosis 1

Gene ID: 22999116837

UniProt: Q86UR5, Q99NE5

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity