PSMB7 antibody (AA 150-200)

Catalog No. ABIN7453543

Product Details anti-PSMB7 Antibody

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Binding Specificity: AA 150-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-PSMB7 Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine

Purification: Affinity Purified

Immunogen: Between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PSMB7

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Alternative Name: PSMB7 (PSMB7 Products)

Synonyms: DDBDRAFT_0185624 antibody, DDBDRAFT_0232933 antibody, DDB_0185624 antibody, DDB_0232933 antibody, AU020723 antibody, MC14 antibody, Z antibody, 20S proteasome subunit beta-7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog antibody, proteasome subunit beta 7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 antibody, proteasome (prosome, macropain) subunit, beta type 7 antibody, psmB7 antibody, psmb7.S antibody, PSMB7 antibody, Psmb7 antibody

Background: Background: PSMB7 [proteasome (prosome, macropain) subunit, beta type,7] is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit [taken from NCBI Entrez Gene (Gene ID: 5695)].

Gene ID: 5695

NCBI Accession: NP_002790

UniProt: Q99436

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA