Recombinant CD4 antibody (AA 26-397)
Quick Overview for Recombinant CD4 antibody (AA 26-397) (ABIN7455077)
Target
See all CD4 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 26-397
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Purpose
- Rabbit anti-CD4 Recombinant Monoclonal Antibody [BL-155-1C11]
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Immunogen
- residues 26-397 (ECD)
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Isotype
- IgG
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Application Notes
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IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 20 μL/mg lysate
WB: 17:40:00
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- CD4
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Alternative Name
- CD4
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Background
- Background: CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. CD4 is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system [taken from NCBI Entrez Gene (Gene ID: 920)].
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Gene ID
- 920
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NCBI Accession
- NP_000607
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UniProt
- P01730
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Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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