CD47 antibody (Biotin)

Catalog No. ABIN7456647

This Mouse Monoclonal antibody specifically detects CD47 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD47 antibody (Biotin) (ABIN7456647)

Target: CD47

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD47 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: CC2C6D4

Product Details anti-CD47 Antibody (Biotin)

Isotype: IgG1, kappa

Application Details

Application Notes: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Comment:

Matching Isotype Control: Biotin Mouse Rat IgG1, κ Isotype Control (ABIN7469769)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for CD47

Target: CD47

Alternative Name: CD47

Background: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP,CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47, in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.

Gene ID: 961

UniProt: Q08722