DUOX1 antibody

Catalog No. ABIN7464356

Product Details anti-DUOX1 Antibody

Target: DUOX1 (Dual Oxidase 1 (DUOX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DUOX1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549 , H1299 , HCT116 , unboiled A431 , A431 membrane extract

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DUOX1

Target: DUOX1 (Dual Oxidase 1 (DUOX1))

Alternative Name: dual oxidase 1 (DUOX1 Products)

Synonyms: Udx1 antibody, duox1 antibody, LNOX1 antibody, NOXEF1 antibody, THOX1 antibody, 9930101G15Rik antibody, AW987690 antibody, Duox2 antibody, LNOX2 antibody, NOXEF2 antibody, P138-TOX antibody, THOX2 antibody, dual oxidase 1 antibody, dual oxidase antibody, duox1 antibody, DUOX1 antibody, duox antibody, LOC5569378 antibody, Duox1 antibody

Background: Dual oxidase 1 , LNOX1 , NOXEF1 , THOX1,The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]

Molecular Weight: 177 kDa

Gene ID: 53905

UniProt: Q9NRD9