JAG2 antibody (N-Term)

Catalog No. ABIN7469434

The Rabbit Polyclonal anti-JAG2 antibody has been validated for WB and IHC (p). It is suitable to detect JAG2 in samples from Human.

Quick Overview for JAG2 antibody (N-Term) (ABIN7469434)

Target: JAG2 (Jagged 2 (JAG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-JAG2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Jagged 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.47 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Alternative Name: Jagged 2

Background:

Synonyms: jagged canonical Notch ligand 2 , HJ2 , SER2

Background: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 133 kDa

Gene ID: 3714

UniProt: Q9Y219

Pathways: Notch Signaling, Sensory Perception of Sound