TSPY-Like 2 antibody (AA 251-350) (HRP)

Catalog No. ABIN722254

Product Details anti-TSPY-Like 2 Antibody (HRP)

Target: TSPY-Like 2 (TSPYL2)

Binding Specificity: AA 251-350

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPY-Like 2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DENTT

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSPY-Like 2

Target: TSPY-Like 2 (TSPYL2)

Alternative Name: DENTT (TSPYL2 Products)

Synonyms: CDA1 antibody, CINAP antibody, CTCL antibody, DENTT antibody, HRIHFB2216 antibody, NP79 antibody, SE204 antibody, TSPX antibody, RGD1563283 antibody, cda1 antibody, ctcl antibody, np79 antibody, tspx antibody, cinap antibody, dentt antibody, se204 antibody, DXBwg1396e antibody, DXHXS1008E antibody, E130307F10Rik antibody, QflA-13812 antibody, QmoA-12404 antibody, TSPY-like protein 2 antibody, TSPY like 2 antibody, TSPY-like 2 antibody, TSPY-like 2 L homeolog antibody, TSPYL2 antibody, Tspyl2 antibody, tspyl2 antibody, Exig_1158 antibody, tspyl2.L antibody

Background:

Synonyms: Testis-specific Y-encoded-like protein 2, TSPY-like protein 2, Cell division autoantigen 1, Cutaneous T-cell lymphoma-associated antigen se20-4, CTCL-associated antigen se20-4, Differentially-expressed nucleolar TGF-beta1 target protein, Nuclear protein of 79 kDa, NP79, TSPYL2, CDA1, DENTT, TSPX, HRIHFB2216

Background: Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.

Gene ID: 64061

UniProt: Q9H2G4

Pathways: ER-Nucleus Signaling