TDGF1 antibody

Catalog No. ABIN723291

The Mouse Monoclonal anti-TDGF1 antibody (Clone 2B11) (ABIN723291) specifically detects TDGF1 in WB, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for TDGF1 antibody (ABIN723291)

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TDGF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 2B11

Product Details anti-TDGF1 Antibody

Purpose: CRIPTO (2B11) Monoclonal Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human Teratocarcinoma-derived growth factor 1

Isotype: IgG

Application Details

Application Notes: WB(1:500-1000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: CRIPTO

Background:

Synonyms: CRIPTO, CRIPT, CR, CRGF, Cripto 1, Cripto-1, Cripto 1 growth factor, Cripto-1 growth factor, Cripto1, Cripto1 growth factor, Epidermal growth factor like cripto protein CR1, Epidermal growth factor-like cripto protein CR1, TDGF 1, TDGF-1, TDGF1, Teratocarcinoma derived growth factor 1, Teratocarcinoma-derived growth factor 1, teratocarcinoma-derived growth factor 1 isoform 1 precursor, TDGF1_HUMAN.

Background: This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

Gene ID: 6997

Pathways: EGFR Signaling Pathway