TDGF1 antibody (Biotin)

Catalog No. ABIN723353

The Mouse Monoclonal anti-TDGF1 antibody is suitable to detect TDGF1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for TDGF1 antibody (Biotin) (ABIN723353)

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TDGF1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1F10

Product Details anti-TDGF1 Antibody (Biotin)

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human CRIPTO/ Teratocarcinoma-derived growth factor 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: CRIPTO

Background:

Synonyms: CRIPTO, CRIPT, CR, CRGF, Cripto 1, Cripto-1, Cripto 1 growth factor, Cripto-1 growth factor, Cripto1, Cripto1 growth factor, Epidermal growth factor like cripto protein CR1, Epidermal growth factor-like cripto protein CR1, TDGF 1, TDGF-1, TDGF1, Teratocarcinoma derived growth factor 1, Teratocarcinoma-derived growth factor 1, teratocarcinoma-derived growth factor 1 isoform 1 precursor, TDGF1_HUMAN.

Background: This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

Gene ID: 6997

Pathways: EGFR Signaling Pathway