Alpha, beta Synuclein (AA 122-140) antibody
-
- Target
- Alpha, beta Synuclein
-
Binding Specificity
- AA 122-140
-
Reactivity
- Mouse, Rat
-
Host
- Mouse
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Dog,Cow,Sheep,Pig,Horse,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Alpha-Synuclein
- Isotype
- IgG
-
-
- Application Notes
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Alpha, beta Synuclein
- Alternative Name
- alpha + beta Synuclein
- Background
-
Synonyms: PD1, NACP, PARK1, PARK4, Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, SNCA
Background: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
- Gene ID
- 6622
- UniProt
- P37840
-