PP2A alpha/beta antibody (AA 205-309) (HRP)
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- Target See all PP2A alpha/beta (PP2A A/B) products
- PP2A alpha/beta (PP2A A/B)
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Binding Specificity
- AA 205-309
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PP2A alpha/beta antibody is conjugated to HRP
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PP-2A
- Isotype
- IgG
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anti-PP2A alpha/beta (PP2A A/B) (AA 205-309) antibody
PP2A A/B Reactivity: Human, Mouse WB, IF (cc), IF (p), ELISA, FACS, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-PP2A alpha/beta (PP2A A/B) (pTyr307) antibodyPP2A A/B Reactivity: Human, Rat WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-PP2A alpha/beta (PP2A A/B) antibodyPP2A A/B Reactivity: Human, Mouse WB, IP Host: Mouse Monoclonal unconjugated
anti-PP2A alpha/beta (PP2A A/B) antibodyPP2A A/B Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Drosophila melanogaster, Hamster, Xenopus laevis, Horse, Insect, Bat, Monkey, Chicken, Cow, Pig, Dog, Rabbit WB, ELISA Host: Goat Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PP2A alpha/beta (PP2A A/B)
- Alternative Name
- PP2A alpha / beta (PP2A A/B Products)
- Background
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Synonyms: RP-C, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, PPP2CA
Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
- Gene ID
- 5515
- UniProt
- P67775
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