RASAL3 antibody (AA 48-925)

Catalog No. ABIN7601841

This Rabbit Polyclonal antibody specifically detects RASAL3 in WB, IHC, ELISA and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for RASAL3 antibody (AA 48-925) (ABIN7601841)

Target: RASAL3 (RAS Protein Activator Like 3 (RASAL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASAL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-RASAL3 Antibody

Binding Specificity: AA 48-925

Purpose: Anti-RASAL3 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human RASAL3 shares 82.4% amino acid (aa) sequence identity with mouse RASAL3.

Characteristics: Anti-RASAL3 Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RASAL3 recombinant protein (Position: R48-Q925). Human RASAL3 shares 82.4% amino acid (aa) sequence identity with mouse RASAL3.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RASAL3

Target: RASAL3 (RAS Protein Activator Like 3 (RASAL3))

Alternative Name: RASAL3

Background:

Background: This gene belongs to the Ras GTPase-activating proteins (RasGAP) family and encodes a protein with pleckstrin homology (PH), C2, and Ras GTPase-activation protein (RasGAP) domains. This protein is localized near or at the plasma membrane when expressed exogenously. Reduced expression of this gene in some cell lines resulted in increased levels of the active form of Ras (Ras-GTP), suggesting that this gene may play a role in negatively regulating the Ras signaling pathway. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: RAS protein activator like 3

Molecular Weight: 112 kDa

Gene ID: 64926

UniProt: Q86YV0