MDM2 antibody (pSer166)

Catalog No. ABIN7603279

The Rabbit Monoclonal anti-MDM2 antibody is suitable to detect MDM2 in samples from Human. It has been validated for WB and IHC.

Quick Overview for MDM2 antibody (pSer166) (ABIN7603279)

Target: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MDM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 29M35

Product Details anti-MDM2 Antibody

Binding Specificity: pSer166

Purpose: Anti-Phospho-MDM2 (S166) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-MDM2 Rabbit Monoclonal Antibody (ABIN7603279). Tested in WB, IHC applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-MDM2 (S166)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for MDM2

Target: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Alternative Name: MDM2

Background:

Synonyms: Retinoblastoma-associated protein,p105-Rb,pRb,Rb,pp110,RB1,

Tissue Specificity: Expressed in the retina.

Molecular Weight: 90-100 kDa

UniProt: Q00987

Pathways: p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway