CDC42 antibody (pSer71)

Catalog No. ABIN7603355

The Rabbit Monoclonal anti-CDC42 antibody (Clone IBB-3) (ABIN7603355) specifically detects CDC42 in WB. The antibody is reactive with Human samples.

Quick Overview for CDC42 antibody (pSer71) (ABIN7603355)

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDC42 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: IBB-3

Product Details anti-CDC42 Antibody

Binding Specificity: pSer71

Purpose: Anti-Phospho-Rac1/Cdc42 (Ser71) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-Rac1/Cdc42 (Ser71) Rabbit Monoclonal Antibody (ABIN7603355). Tested in WB application. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-Rac1/Cdc42 (Ser71)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CDC42

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Alternative Name: CDC42

Background:

Synonyms: Cell division control protein 42 homolog,G25K GTP-binding protein,CDC42,

Tissue Specificity: Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level). .

Molecular Weight: 70, 75 kDa

Pathways: MAPK Signaling, Microtubule Dynamics, RTK Signaling, WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling