GSK3 alpha antibody (pTyr216, pTyr279)

Catalog No. ABIN7603444

The Rabbit Monoclonal anti-GSK3 alpha antibody has been validated for WB, IHC, IP, IF and ICC. It is suitable to detect GSK3 alpha in samples from Human, Mouse and Rat.

Quick Overview for GSK3 alpha antibody (pTyr216, pTyr279) (ABIN7603444)

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GSK3 alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: IFB-7

Product Details anti-GSK3 alpha Antibody

Binding Specificity: pTyr216, pTyr279

Purpose: Anti-Phospho-GSK3 (alpha + beta) (Y216 + Y279) GSK3A Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-GSK3 (alpha + beta) ( + ) GSK3A Rabbit Monoclonal Antibody (ABIN7603444). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-GSK3 (alpha + beta) (Y216 + Y279)

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for GSK3 alpha

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Alternative Name: GSK3A

Background:

Synonyms: Glycogen synthase kinase-3 alpha,GSK-3 alpha,2.7.11.26,Serine/threonine-protein kinase GSK3A,2.7.11.1,GSK3A,

Tissue Specificity: Restricted to the nervous system. Highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. .

Molecular Weight: 40 kDa

UniProt: P49840

Pathways: PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect