PDX1 antibody

Catalog No. ABIN7605902

The Rabbit Monoclonal anti-PDX1 antibody (Clone AEC-16) (ABIN7605902) specifically detects PDX1 in WB, IHC, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for PDX1 antibody (ABIN7605902)

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PDX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AEC-16

Product Details anti-PDX1 Antibody

Purpose: Anti-PDX1/Ipf1 Rabbit Monoclonal Antibody

Characteristics: Anti-PDX1/Ipf1 Rabbit Monoclonal Antibody (ABIN7605902). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human PDX1

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Alternative Name: PDX1

Background:

Synonyms: Pancreas/duodenum homeobox protein 1,PDX-1,Glucose-sensitive factor,GSF,Insulin promoter factor 1,IPF-1,Insulin upstream factor 1,IUF-1,Islet/duodenum homeobox-1,IDX-1,Somatostatin-transactivating factor 1,STF-1,PDX1,IPF1, STF1,

Tissue Specificity: Duodenum and pancreas (Langerhans islet beta cells and small subsets of endocrine non-beta-cells, at low levels in acinar cells).

Molecular Weight: 42 kDa

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location