JAK1 antibody (Biotin)

Catalog No. ABIN7632217

This Rabbit Polyclonal antibody specifically detects JAK1 in WB, IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for JAK1 antibody (Biotin) (ABIN7632217)

Target: JAK1 (Janus Kinase 1 (JAK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAK1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-JAK1 Antibody (Biotin)

Purpose: Biotin-Linked Polyclonal Antibody to Janus Kinase 1 (JAK1)

Specificity: The antibody is a rabbit polyclonal antibody raised against JAK1. It has been selected for its ability to recognize JAK1 in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: PAC551Hu01Polyclonal Antibody to Janus Kinase 1 (JAK1)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL Immunohistochemistry: 5-20 μg/mL Immunocytochemistry: 5-20 μg/mL Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Target Details for JAK1

Target: JAK1 (Janus Kinase 1 (JAK1))

Alternative Name: Janus Kinase 1

Background: JAK1A, JAK1B, JTK3, Tyrosine-protein kinase JAK1

UniProt: P23458

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response