HSPB6 antibody (AA 6-80) (Biotin)
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- Target See all HSPB6 Antibodies
- HSPB6 (Heat Shock Protein, alpha-Crystallin-Related, B6 (HSPB6))
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Binding Specificity
- AA 6-80
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSPB6 antibody is conjugated to Biotin
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Cow
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HSP20
- Isotype
- IgG
- Top Product
- Discover our top product HSPB6 Primary Antibody
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- Application Notes
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- HSPB6 (Heat Shock Protein, alpha-Crystallin-Related, B6 (HSPB6))
- Alternative Name
- HSP20 (HSPB6 Products)
- Synonyms
- Hsp20 antibody, p20 antibody, AA387366 antibody, Gm479 antibody, HSP20 antibody, heat shock protein family B (small) member 6 antibody, heat shock protein, alpha-crystallin-related, B6 antibody, heat shock protein family B (small) member 6 L homeolog antibody, heat shock protein, alpha-crystallin-related, b6 antibody, HSPB6 antibody, Hspb6 antibody, hspb6.L antibody, hspb6 antibody
- Background
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Synonyms: Heat Shock Protein 20, FLJ32389, Heat shock 20 kDa like protein p20, Heat shock protein alpha crystallin related B6, Heat shock protein beta 6, Hspb6, HSPB6_HUMAN.
Background: Hsp20 is a small heat shock protein related to Hsp25, Hsp27 and may form different hetercomplexes with these proteins. The specific physiological function of Hsp20 is not yet known. It is distributed ubiquitously in tissues, but is found in higher levels in skeletal, smooth and heart muscle. Under normal conditions, Hsp20 is diffusely distributed in the cytosol, but under heat stress conditions, it translocates to the nucleus. Unlike other heat shock proteins the amount of Hsp20 does not increase after heat shock. The Hsp20 was demonstrated to constitute up to 1.3 % of the total cellular protein in vertebrate tissues, especially in muscle, and its expression is related to muscle contraction, specifically in slow-twitch muscle. Hsp20 may form different heterocomplexes with other Hsp's, such as alpha-crystalline and Hsp25. Phosphorylated form of Hsp20 is proposed to interact with monomeric actin whereas dephosphorylated form binds polymeric actin filaments. In normal conditions Hsp20 is diffusely disturbed in cytosol but under the heat stress it undergoes translocation to membrane fraction.
- Gene ID
- 126393
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