Integrin beta 2 antibody (PE)

Catalog No. ABIN7670232

This Mouse Monoclonal antibody specifically detects Integrin beta 2 in FACS. It exhibits reactivity toward Human.

Quick Overview for Integrin beta 2 antibody (PE) (ABIN7670232)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: IB4

Product Details anti-Integrin beta 2 Antibody (PE)

Purpose: PE Anti-Human CD18 (ITGB2) Antibody[IB4]

Immunogen: E-AB-F09802D

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Handling Advice: Please protected from prolonged exposure to light and do not freeze.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months.

Expiry Date: 12 months

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background: Myeloid cell surface antigen CD33,CD33,Sialic acid-binding Ig-like lectin 3,Siglec-3,gp67,SIGLEC3,CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

UniProt: P20138

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation