Recombinant GZMB antibody (C-Term)

Catalog No. ABIN7795632

The Rabbit Monoclonal anti-GZMB antibody has been validated for WB. It is suitable to detect GZMB in samples from Mouse.

Quick Overview for Recombinant GZMB antibody (C-Term) (ABIN7795632)

Target: GZMB (Granzyme B (GZMB))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GZMB antibody is un-conjugated

Application: Western Blotting (WB)

Clone: BLR244L

Product Details anti-GZMB Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR244L] - BSA-Free

Purification: Purified

Immunogen: Between 197 and C-terminus

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for GZMB

Target: GZMB (Granzyme B (GZMB))

Alternative Name: Granzyme B

Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]

Gene ID: 14939

UniProt: P04187

Pathways: Apoptosis, Caspase Cascade in Apoptosis