Recombinant KIT antibody (AA 325-375)

Catalog No. ABIN7795658

This Rabbit Monoclonal antibody specifically detects KIT in WB, IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for Recombinant KIT antibody (AA 325-375) (ABIN7795658)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KIT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR263L

Product Details anti-KIT Antibody

Binding Specificity: AA 325-375

Purpose: Rabbit anti-c-Kit Recombinant Monoclonal Antibody [BLR263L]

Purification: Purified

Immunogen: Between 325 and 375

Isotype: IgG

Application Details

Application Notes: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: c-Kit

Background: C-Kit is the receptor for stem cell factor (mast cell growth factor). It is a transmembrane receptor with tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of the c-Kit receptor and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P10721].

Gene ID: 3815

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity