The Rabbit Monoclonal anti-RUNX2 antibody (Clone BLR360N) (ABIN7795798) specifically detects RUNX2 in WB, IHC, IP and ICC.
The antibody is reactive with Human and Mouse samples.
RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with a Runt DNA-binding domain. RUNX2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. RUNX2 can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. [provided by RefSeq, Jul 2016] [taken from NCBI Entrez Gene (Gene ID: 860)].