Recombinant CD47 antibody

Catalog No. ABIN7828085

The Rabbit Monoclonal anti-CD47 antibody is suitable to detect CD47 in samples from Human. It has been validated for WB.

Quick Overview for Recombinant CD47 antibody (ABIN7828085)

Target: CD47

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD47 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A652

Product Details anti-CD47 Antibody

Purpose: Recombinant CD47 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CD47 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD47

Target: CD47

Alternative Name: CD47

Background: MER,Protein MER,Leukocyte surface antigen CD,Antigenic surface determinant protein OA,CD47,IAP,MER6,OA3,Integrin-associated protein,Leukocyte surface antigen CD47,Antigenic surface determinant protein OA3,Integrin-associated protein (IAP),Protein MER6,Antigen identified by monoclonal 1D8,CD 47,CD47 antigen,CD47 antigen (Rh-related antigen,CD47 glycoprotein,CD47 Molecule,Integrin Associated Protein,Integrin associated signal transducer,integrin-associated signal transducer),MER 6,OA 3,OTTHUMP00000041152,OTTHUMP00000041153,Rh related antigen,Surface antigen identified by monoclonal 1D8,CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 plays an important role in memory formation and synaptic plasticity in the hippocampus. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interacts with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. CD47 may prevent premature elimination of red blood cells. CD47 may be involved in membrane permeability changes induced following virus infection. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 47-52 kDa

Observed MW: 47-52 kDa

UniProt: Q08722