TNF alpha antibody

Catalog No. ABIN8062981

The Armenian Hamster Monoclonal anti-TNF alpha antibody is suitable to detect TNF alpha in samples from Mouse. It has been validated for FACS.

Quick Overview for TNF alpha antibody (ABIN8062981)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: TN3-19-12

Product Details anti-TNF alpha Antibody

Purpose: AF/LE Purified Anti-Mouse TNF-α Antibody[TN3-19.12]

Purification: >98%, Protein A/G purified

Purity: >98 %

Immunogen: Recombinant Mouse TNF-alpha protein

Isotype: IgG2, kappa

Application Details

Application Notes: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Preservative: Without preservative

Handling Advice: This preparation contains no preservatives, thus it should be handled under aseptic conditions

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiry Date: 12 months

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF-alpha

Background: Tumor necrosis factor ligand superfamily member,TNFSF,DIF,Tnfa,TNF-a,TNFSF2,Tnlg1f,Tnfsf1a,TNFalpha,TNF-alpha,ICD1,ICD2,Membrane Form,N-terminal fragment,NTF,Tnf,Cachectin,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tnfa,TNF-a,TNFalpha,TNF-alpha,Tnfsf1a,TNFSF2,Tnlg1f,TNFSF2,TNF,TNFa,Tumor necrosis factor alpha (TNF-alpha, TNF- alpha, TNFA ), also known as Cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism. TNF-alpha is produced by several lymphoid cells as well as by astrocytes, endothelial cells, and smooth muscle cells. Mouse TNF-alpha consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 179 aa extracellular domain (ECD). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P06804

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome