TNF alpha antibody

Catalog No. ABIN8063041

This Mouse Monoclonal antibody specifically detects TNF alpha in FACS. It exhibits reactivity toward Human.

Quick Overview for TNF alpha antibody (ABIN8063041)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: MAb11

Product Details anti-TNF alpha Antibody

Purpose: Purified Anti-Human TNF-α Antibody[MAb11]

Purification: >98%, Protein A/G purified

Purity: >98 %

Immunogen: Recombinant Human TNF-alpha protein

Isotype: IgG1, kappa

Application Details

Application Notes: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF-alpha

Background: Tumor Necrosis Factor Ligand Superfamily Member,TNFSF,TNF,DIF,TNF-alpha,TNFA,TNFSF2,TNLG1F,TNF alpha,Cachectin,Tumor Necrosis Factor,Tumor Necrosis Factor Ligand Superfamily Member 2,TNF-a,APC1,APC1 protein,DIF,TNF-alpha,TNFA,TNFSF2,Differentiation inducing factor,Macrophage cytotoxic factor,macrophage derived,member 2,Membrane Form,monocyte derived,soluble form,sTNFA,TNF superfamily,Tumor necrosis factor alpha,This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P01375

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome