IFNA1 antibody

Catalog No. ABIN7865669

This Mouse Monoclonal antibody specifically detects IFNA1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for IFNA1 antibody (ABIN7865669)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: Feb-48

Product Details anti-IFNA1 Antibody

Purpose: anti-Interferon α 1 mouse monoclonal, 2-48, purified

Purification: affinity chromatography

Immunogen: E.coli derived recombinant human interferon alpha 1

Isotype: IgG1 kappa

Application Details

Application Notes:

WB_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Alternative Name: Interferon alpha 1

Background: The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNα family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNα are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNα include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNα are now known and seem to be expressed on most cell types. 2-48 Is specific for human interferon α 1 and does not cross react with human interferon α 2. Positive control: Human interferon α 1.

Pathways: JAK-STAT Signaling, Hepatitis C