MICA antibody (PE)
Quick Overview for MICA antibody (PE) (ABIN7867369)
Target
See all MICA AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- PE-conjugated Anti-MICA antibody(DM157), Rabbit mAb
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG
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Application Notes
- Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2°C-8°C for 6 months
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Expiry Date
- 6 months
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Alternative Name
- MICA
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Background
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Synonyms: MIC-A, PERB11.1
Target Background: This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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UniProt
- Q29983
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Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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