NLRP7 antibody (AA 1-169)

Catalog No. ABIN7868239

The Rabbit Polyclonal anti-NLRP7 antibody (ABIN7868239) specifically detects NLRP7 in ELISA, WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for NLRP7 antibody (AA 1-169) (ABIN7868239)

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NLRP7 Antibody

Binding Specificity: AA 1-169

Purpose: NLRP7 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-L169) was used as the immunogen for the NLRP7 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NLRP7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NLRP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NLRP7

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Alternative Name: NLRP7

Background: NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q8WX94

Pathways: Inflammasome